Ofloxacin + Metronidazole + Simethicone is a combination of three antibiotics: Ofloxacin , Metronidazole and Simethicone which treat diarrhoea. Ofloxacin kills bacteria by preventing them from reproducing and repairing themselves. Metronidazole kills other microorganisms in addition to bacteria by damaging the DNA. Together, they treat your infection effectively. Simethicone is an antifoaming medicine which disintegrates gas bubbles and allows easy passage of gas.